http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109824601-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-10 |
filingDate | 2017-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109824601-B |
titleOfInvention | Method for synthesizing chiral cyclic urea through asymmetric hydrogenation of iridium-catalyzed 2-hydroxypyrimidine compound |
abstract | The invention provides a chiral ring synthesized by asymmetric hydrogenation of an iridium-catalyzed 2-hydroxypyrimidine compoundA process for the preparation of urea-like compounds, in the formula: r is C1-C6 alkyl or aryl; r' is aryl, heteroaryl or alkyl containing substituent groups, wherein the substituent groups are F, Cl and CF 3 Me and MeO. The synthesized chiral cyclic urea has an enantiomeric excess of 96%. The method has the advantages of simple, convenient, practical and feasible operation, high yield, environment friendliness, commercial availability of the catalyst, mild reaction conditions and potential practical application value. |
priorityDate | 2017-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.