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filingDate 2019-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109821075-B
titleOfInvention Biological material, preparation method thereof and application of biological material as bone defect repair material
abstract The invention discloses a biological material, a preparation method thereof and application of the biological material as a bone defect repair material, and belongs to the technical field of medical biological materials. The preparation method comprises the steps of adding a photoinitiator solution into an aqueous solution containing methacrylic anhydride gelatin, wherein the photoinitiator solution is a photoinitiator 819 solution or a mixed solution of the photoinitiator 819 and the photoinitiator 184; carrying out extrusion type 3D biological printing on the printing slurry, and carrying out ultraviolet irradiation on the slurry when the slurry is extruded; preferably, the aqueous solution containing methacrylic anhydride gelatin also contains carboxymethyl chitosan; preferably, the printing is done followed by chemical crosslinking; preferably, an inorganic bioceramic material is added to the printing paste. The method has the advantages of simple components, stable printing process, high precision, high crosslinking degree, high crosslinking speed and good biocompatibility of the stent, can be used as a carrier of medicines or other functional components, and has very wide application prospect in the field of bone defect repair.
priorityDate 2019-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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