http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109820821-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-405 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4172 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-02 |
| filingDate | 2019-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109820821-B |
| titleOfInvention | Oral care solution capable of effectively inhibiting bacteria |
| abstract | The invention relates to an oral care solution with effective bacteriostasis and a preparation method thereof, wherein the oral care solution comprises a nano bacteriostasis factor and an adhesion reinforcing agent; the nano bacteriostatic factor is D-tryptophan and D-histidine nano encapsulated micelle particles prepared by a dialysis technology; the adhesion enhancer is a combination of hydroxypropyl cellulose, hyaluronic acid and glycerol. The amphiphilic polymer is adopted to improve the stability of D-tryptophan and D-histidine, promote the mucosal permeation of the D-tryptophan and the D-histidine, slow down the release of the D-tryptophan and the D-histidine, the release time is up to 48 hours, and the biological membrane degradation effect of the D-tryptophan and the D-histidine is prolonged; the hydroxypropyl cellulose, the hyaluronic acid and the glycerol in the optimal proportion are selected as the adhesion reinforcing agent, so that the adhesion time of the antibacterial factors in the oral care solution on the oral mucosa surface can be prolonged, the medicine utilization rate is improved, the action time of the antibacterial factors in the oral cavity is prolonged, and a better antibacterial effect is exerted. |
| priorityDate | 2019-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.