http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109810085-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D309-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 |
filingDate | 2019-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109810085-B |
titleOfInvention | The preparation method of ACC inhibitor and its intermediate |
abstract | The present invention relates to organic compound synthesis technical fields, more particularly, to the preparation method of a kind of ACC inhibitor and its intermediate.The preparation method of the intermediate of ACC inhibitor includes the following steps: that a, chemical compounds I carry out halogenating reaction and obtain compound ii;B, compound ii and oxinane -4- alcohol carry out substitution reaction and obtain compound III;C, compound III carries out reduction reaction under reducing agent effect and obtains the intermediate V of compounds Ⅳ and ACC inhibitor, and separation and/or further hydrogenating reduction obtain V sterling of intermediate of ACC inhibitor.Start material of the invention is cheap, using chemical compounds I as starting material, intermediate is prepared through halogenated, substitution, reduction, hydrogenation reaction, each reaction condition that walks is mild, and high income is suitble to industrialized production. |
priorityDate | 2019-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 128.