http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109810073-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8d5e5f62d4e87d87cefb726a4e1c4406 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-426 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-587 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
| filingDate | 2019-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e64b90a88a7b5492762f55a0ad9a27f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bfef489925ceb3753a253f1d14a44256 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1afc72b771ce6c43a1c4a04d7a5f9c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1bf1cc63b44f9c16e4fabc2bbc8532ba |
| publicationDate | 2019-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109810073-A |
| titleOfInvention | 4-Arylthiazole derivatives and pharmaceutical compositions thereof |
| abstract | The present invention designs and synthesizes a class of 4-arylthiazole derivatives with xanthine oxidase inhibitory activity, and they have the chemical structure of (I), where Y represents O, S, NH; R 1 represents H, C 1 -C 4 alkane; R 2 represents formyl, -(CH 2 ) n CO 2 H or -(CH 2 ) n COR 5 , wherein n=0～4, R 5 is C 1 ～C 4 alkoxy or amino acid ; R 3 represents formyl, cyano, nitro, amino or hydroxylamino; R 4 represents C 1 -C 8 linear or branched alkyl, C 2 -C 8 linear or branched alkenyl or co- Conjugated or non-conjugated polyalkenyl, C 2 -C 8 linear or branched alkynyl, or C 2 -C 8 linear or branched conjugated or non-conjugated alkenynyl. This type of 4-arylthiazole compound has the activity of inhibiting xanthine oxidase, can be used for preparing medicines for preventing and treating diseases such as hyperuricemia and gout, and has a wide range of uses in pharmacy. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110204494-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110204494-B |
| priorityDate | 2019-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 106.