http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109806225-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-44 |
| filingDate | 2019-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109806225-B |
| titleOfInvention | Vitamin K1 fat emulsion injection |
| abstract | The invention relates to a vitamin K1 fat emulsion injection. Specifically, the emulsion composition comprises vitamin K1, soybean oil, phospholipid, glycerol and water. The composition is prepared by the processes of preparing water phase, preparing oil phase, preparing coarse emulsion, emulsifying under high pressure, sterilizing under hot pressure and the like. The invention also relates to a method for preparing the emulsion composition and a pharmaceutical application of the emulsion composition, which are used for treating blood coagulation dysfunction diseases caused by blood coagulation factor II, VII, IX and X synthesis disorders caused by vitamin K deficiency or drug intervention interfering with vitamin K activity. The emulsion compositions of the present invention exhibit one or more of the technical effects as described in the specification, for example, the composition can be used at a time of 10mg each time, 1-2 times daily, with a total amount of not more than 40mg in 24 hours, with the dosage and frequency of administration adjusted according to the prothrombin time response or clinical symptoms; the administration mode is intravenous administration, and the infusion can be undiluted, injected by intravenous injection directly or diluted by 5% glucose injection and then infused by intravenous drip. |
| priorityDate | 2019-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 109.