http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109796441-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 |
| filingDate | 2019-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109796441-B |
| titleOfInvention | Preparation method of impurity A of tipyrimidine hydrochloride |
| abstract | The invention belongs to the technical field of chemical pharmacy, and relates to a preparation method of an impurity A of tipyrimidine hydrochloride. The preparation method comprises a synthesis reaction, wherein the synthesis reaction is to perform hydrolysis reaction on 5-chloro-6- [ (2-imine-1-pyrrolidine) methyl ] uracil hydrochloride and an aqueous solution of alkali. The preparation method of the impurity A of the tipyrimidine hydrochloride can synthesize and prepare the impurity A of the tipyrimidine hydrochloride with simple operation, easily obtained raw materials, high yield and easy purification, so that the prepared impurity A is used as an impurity standard substance in the detection and analysis of finished products of the tipyrimidine hydrochloride and is used for the quality control of the tipyrimidine hydrochloride. According to the preparation method, after the impurity A of the Tibi pyrimidine hydrochloride is synthesized, a high-purity target product can be obtained only by simple filtration and washing. |
| priorityDate | 2019-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 352.