http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109796362-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b845f17380894f496a6e241d2e577c88 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-02 |
| filingDate | 2019-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce0530b4f5bbadd6595530107f07f069 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bee829fdb1469f86943fa1884d7ae48e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b15d43dcfe913d4143add24e50e56475 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09b7e8b9608f6bcd2e5f86ee8a7b7f00 |
| publicationDate | 2019-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109796362-A |
| titleOfInvention | A kind of preparation method of 9,10-bis(N-(2,3-dihydroxypropyl) propionamido) anthracene |
| abstract | The invention provides a preparation method of 9,10-bis(N-(2,3-dihydroxypropyl)propionamido)anthracene (DHPA), and relates to the technical field of chemical synthesis. The method comprises the following steps: mixing 9,10-dibromoanthracene, ethyl acrylate, a first palladium catalyst, a ligand, a base and a first organic solvent to carry out a Heck reaction to obtain 9,10-bis(3-ethyl acrylate) Anthracene (compound 2); Compound 2 is mixed with the second palladium catalyst, reducing agent and the second organic solvent, and hydrogenation is carried out to obtain 9,10-two (3-ethyl propionate) anthracene (compound 3); Compound 3 is mixed with 3-amino-1, 2-propanediol and an alcohol solvent, and an amine transesterification reaction is carried out to obtain the final product DHPA. In the preparation of DHPA, the method adopts common reagents, has low cost of raw materials, short preparation process, and yields as high as 85%, is safe and convenient to operate, and is suitable for large-scale industrial production. |
| priorityDate | 2019-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 71.