| abstract |
The present invention provides a tumor antigen polypeptide or a variant thereof with an amino acid sequence shown in SEQ ID NO: 2, which encodes a nucleic acid, a nucleic acid construct comprising the encoded nucleic acid, an expression vector, and a host cell, which presents the nucleic acid on the cell surface. Antigen-presenting cells of tumor antigen polypeptides and their immune effector cells. The present invention also provides the application of the polypeptide, nucleic acid, antigen presenting cell or immune effector cell in diagnosing, preventing and treating cancer. |