http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109771371-B
Outgoing Links
Predicate | Object |
---|---|
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
filingDate | 2019-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109771371-B |
titleOfInvention | Clindamycin phosphate injection and preparation method thereof |
abstract | The invention discloses a clindamycin phosphate injection and a preparation method thereof, wherein the clindamycin phosphate injection comprises the following components of clindamycin phosphate (according to C) 18 H 33 ClN 2 O 5 S) 135-165 mg/ml, DSPE-mPEG 20003-6 mg/ml, sorbitol 0.05-0.1 mg/ml and water for injection. The addition of a proper amount of DSPE-mPEG2000 into the clindamycin phosphate aqueous solution can solubilize the clindamycin phosphate, more importantly, the stability of the clindamycin phosphate aqueous solution is obviously improved, and related substances are only slightly increased even if the clindamycin phosphate aqueous solution is processed at a higher temperature. The clindamycin phosphate injection disclosed by the invention can be sterilized by adopting circulating steam, is high-temperature resistant and has better stability. |
priorityDate | 2019-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.