http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109761944-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_19387a55a374d74b9ebd1f5a4a5c9a92 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-665 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4433 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-352 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-655 |
| filingDate | 2019-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6cfd73b73747990070ac76b6c4e29694 |
| publicationDate | 2019-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109761944-A |
| titleOfInvention | A kind of chrysin amide derivatives and preparation method thereof and medical usage |
| abstract | The present invention relates to field of pharmaceutical chemistry technology, and in particular to the preparation method and medical usage of a kind of chrysin amide derivatives and this analog derivative.For the structural formula of chrysin amide derivatives of the invention as shown in formula I, the substituent R in the compound is a series of acylamino-s.The chrysin amide derivatives proposed in the present invention have the characteristics that good water-soluble, stability and pharmacological activity, the preparation method of every kind of chrysin amide derivatives is identical, bromoacetate will be connected on 7 hydroxyls of chrysin, then it is hydrolyzed, finally respectively with a series of amide compounds occur it is amide condensed react, obtain a series of chrysin amide derivatives.Medicine efficacy screening is that a kind of to have exploitation be the compound of novel anti-gout drugs prospect the experimental results showed that this kind of compound compared with chrysin, has the function of preferably water-soluble and preferably anti-trioxypurine, antigout inflammation. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112574160-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113321634-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112574160-B |
| priorityDate | 2019-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 332.