http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109761880-A

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fdb18a8434600b02186f0103554fb2be
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-88
filingDate 2019-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41ceb0f34c1cb91d653184f904d7c25b
publicationDate 2019-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109761880-A
titleOfInvention Synthetic method of carprofen and its intermediates
abstract A synthetic method of carprofen, (1) 2-(3-bromo-4-chlorophenyl) propionic acid reacts with p-nitroaniline to generate a compound shown in formula C-1; (2) the compound shown in formula C-1 generates a compound shown in formula C-2 through reduction reaction; (3) compound shown in formula C-2 is through diazotization reaction, and the mixture of compound shown in compound shown in formula B-3 and by-product B-31 is prepared; (4) the mixture of the compound shown in formula B-3 and the compound shown in by-product B-31 is processed to obtain the compound shown in formula B-3; (5) compound shown in formula B-3 generates carprofen shown in formula A through reaction;
priorityDate 2019-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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