http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109758483-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-155 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-02 |
| filingDate | 2019-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109758483-B |
| titleOfInvention | Preparation method of mouse chronic atrophic gastritis model |
| abstract | The preparation method of the mouse model of chronic atrophic gastritis, according to the body weight of the mice, N-methyl-N-nitro-nitrosoguanidine is perfused, and low-content ammonia water is used for feeding and drinking water; N-methyl-N-nitro- Helicobacter pylori positive for CagA and VagA was administered after nitrosoguanidine intervention; mice were fasted before intragastric administration, and fasted after intragastric administration; male and female mice were sampled, and gastric mucosal histopathological examinations were performed, and gastric mucosal histopathological examinations were performed. Helicobacter pylori was isolated and cultured from the mucosa to confirm the colonization and inflammation of Helicobacter pylori. This method uses mice to construct chronic atrophic gastritis, with simple operation, low cost, short cycle, high success rate, stable pathological changes, strong reproducibility, and outstanding substantive characteristics, which can be used for the study of chronic atrophic gastritis caused by Helicobacter pylori infection. Atrophic gastritis, gastric cancer and other diseases provide good animal models. |
| priorityDate | 2018-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 188.