http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109748982-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-715 |
| filingDate | 2019-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109748982-B |
| titleOfInvention | Preparation method and application of inonotus obliquus polysaccharide |
| abstract | The invention discloses a preparation method of inonotus obliquus polysaccharide, which separates and purifies polysaccharide components with antioxidant and anti-aging functions from inonotus obliquus by using methods of water extraction and alcohol precipitation, repeated freeze thawing, deproteinization, dialysis, freeze drying, affinity chromatography and the like; the polysaccharide component of Inonotus obliquus has strong antioxidant activity; inonotus obliquus polysaccharide pretreatment can inhibit proliferation inhibition and apoptosis of rat aortic smooth muscle cells induced by etoposide, and inhibit increase of cell aging beta-galactosidase activity level, aging-related heterochromatin aggregation and mitochondrial membrane potential decrease caused by etoposide; inonotus obliquus polysaccharide pretreatment can inhibit etoposide-induced increase in p53, p21, p16 protein and mRNA expression levels. The inonotus obliquus polysaccharide component prepared by the method has good antioxidant and anti-aging activities, and has wide application prospect as a novel anti-aging protective medicine. |
| priorityDate | 2019-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 215.