http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109748905-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D257-04 |
| filingDate | 2019-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109748905-B |
| titleOfInvention | Azide ion treatment method, non-genotoxic impurity sartan bulk drug and intermediate thereof |
| abstract | The invention discloses a method for treating azide ions in a system and application of the method in preparing a compound which has no genotoxic impurity and tetrazole groups. The method is to treat azide ions contained in the system with hydrogen peroxide. The method is used for preparing the compound with the tetrazole group, and the preparation method comprises the following steps: and reacting the compound containing the cyano group with azide, adding hydrogen peroxide after the reaction is finished, and quenching to remove excessive sodium azide to further obtain the compound containing the tetrazole group. The compound prepared by the method does not contain genotoxic impurities. The method is simple to operate, mild in reaction conditions and suitable for industrial production. |
| priorityDate | 2019-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 101.