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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c44d4895aa6201081614e533647ab2dc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e9078cf4fb5cd6f469d285ea16c47fe8
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-353
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704
filingDate 2017-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_547dad6ecce9bb716b512685d77d64c8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6573538ed401f757d7e07035703179a1
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publicationDate 2019-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109745333-A
titleOfInvention A kind of pharmaceutical composition for bladder cancer treatment and application thereof
abstract The present application discloses a pharmaceutical composition for bladder cancer treatment and its application. The pharmaceutical composition of the present application for bladder cancer treatment is composed of doxorubicin and epigallocatechin gallate as active ingredients. The pharmaceutical composition of the present application utilizes the synergistic anti-bladder cancer effect of EGCG and DOX, which not only reduces the overall cardiotoxicity of the pharmaceutical composition, but also has less toxic and side effects on normal bladder urothelial cells. Compared with the single use of DOX, the pharmaceutical composition of the present application has a better inhibitory effect on the growth of bladder cancer cells, not only can better inhibit the migration and infection of bladder cancer cells, but also has a better ability to induce apoptosis of bladder cancer cells Effect. The pharmaceutical composition of the present application provides a new drug with better anti-cancer effect and less toxicity for the treatment of bladder cancer.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115887443-A
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priorityDate 2017-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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