http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109734851-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F289-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F220-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F220-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-22 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F289-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-28 |
filingDate | 2018-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109734851-B |
titleOfInvention | Temperature-sensitive polymer, synthesis method thereof and temperature-sensitive injectable hydrogel |
abstract | The invention discloses a temperature-sensitive polymer, a synthesis method thereof and temperature-sensitive injectable hydrogel. When the temperature-sensitive polymer is prepared, GelMA and UPyMA are synthesized; then UPyMA, GelMA and MEO n Dispersing three monomers MA into an alkaline aqueous solution with the pH value of 8-11, removing oxygen, adding a redox initiator or a water-soluble initiator at room temperature to perform polymerization reaction until the reaction is complete, purifying the product, and removing the solvent to obtain the temperature-sensitive polymer. The temperature-sensitive polymer can be used for preparing injectable aqueous phase temperature-sensitive polymer sol under the normal pressure environment of not higher than the corresponding low critical phase transition temperature and not lower than the water solidification temperature, and the sol can immediately form gel above the corresponding low critical phase transition temperature. The temperature-sensitive injectable hydrogel has dynamic mechanical properties and good biocompatibility, and can be applied to biomedical fields such as tissue engineering, drug controlled release, cell three-dimensional culture and the like. |
priorityDate | 2018-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 70.