http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109734779-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_531a4e7d67d9993d918bb6a4fc905235 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2018-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99b13607d2ad6047748cd510d85a12c1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ed834845fae57b0ba33750f6a939269 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c1d1b2b26a3a8180e252426414ddbbf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ab168c1634bf13e84b74688a4fc3220 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_547d31de241b6a9c1765c4089bda8a72 |
| publicationDate | 2019-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109734779-A |
| titleOfInvention | It is a kind of target Tie-1 polypeptide and its application |
| abstract | The invention discloses a kind of polypeptide for targeting Tie-1 and its application, the core sequence of polypeptide is the polypeptide of 15 amino acid composition.Polypeptide of the present invention and Tie-1 albumen have high affinity (affinity KD < 1 × 10 ‑6 M), can be in conjunction with the extracellular region of Tie-1 protein receptor, and Tie-1 albumen can be effectively closed in protein level and cellular level, the combination of Tie-1 albumen and homoreceptor Tie-2 is prevented, there is good bioactivity.The polypeptide can be individually or with other anti-tumor angiogenesis drug conjunctive uses in the preparation of the drug for the treatment of entity tumor, or in preparation for targeting Tie-1 tracer. |
| priorityDate | 2018-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 69.