http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109721523-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-08 |
| filingDate | 2018-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109721523-B |
| titleOfInvention | Indoline derivative and preparation method thereof |
| abstract | The invention provides a method for synthesizing indoline derivatives, which comprises the steps of taking oxamide derivatives as raw materials, adding a catalyst, and under the conditions of a solvent, a peroxide oxidant and an additive, realizing an oxamide-induced intramolecular C-N bonding reaction to synthesize the indoline derivatives, wherein the solvent is one of 1, 2-dichloroethane, chlorobenzene, toluene, m-xylene, mesitylene, dimethyl sulfoxide, 1, 4-dioxane, tert-amyl alcohol or hexafluoroisopropanol; the catalyst is one of palladium chloride, palladium acetate, cobalt acetate, [1,1' -bis (diphenylphosphino) ferrocene ] palladium dichloride, cobalt acetylacetonate, ferric acetylacetonate, nickel chloride or copper acetate; the peroxide oxidant is one of cumyl hydroperoxide, di-tert-butyl peroxide, tert-butyl peroxybenzoate, dicumyl peroxide and tert-butyl peroxide; the additive is one of silver carbonate, benzoquinone, potassium persulfate, cuprous chloride, ferric chloride or N-methylmorpholine oxide. |
| priorityDate | 2018-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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