http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109718366-A

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_795cb009fbe52eb9be778ed97897534c
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-45
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16
filingDate 2019-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b862ce4493b6cf60050e4bd9b43622da
publicationDate 2019-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109718366-A
titleOfInvention A kind of pharmaceutical composition and its application for treating hepatocellular carcinoma
abstract The invention discloses a kind of pharmaceutical compositions and its application for treating hepatocellular carcinoma, its effective component includes dual tyrosine-(Y)-phosphorylated regulation kinases 3, dual tyrosine-(the Y)-phosphorylated regulation kinases 3 carries out phosphorylation to NCOA3, destroy the combination of NOCA3 and ATF4, cause the inhibition of the transcriptional activity of ATF4, to lower the generation of purine metabolism, the growth and metastasis of tumours in HCC Xenograft Tumor Models is significantly suppressed.
priorityDate 2019-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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