http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109706152-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42d09f1d32f6494531c696ea59219b0d |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
filingDate | 2019-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_508116923f82099ffb58fa147688e028 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3c0c751c4e340bf02a33566095f7a91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bdd708dcdd2c96ac670be54a8a1fcaa0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5753cfefec58448875876a1c38575c5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50a9179b2a3cdaf2f7699092ba630bca |
publicationDate | 2019-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109706152-A |
titleOfInvention | A kind of siRNA for inhibiting the expression of circ_0001017 and its application |
abstract | The invention discloses a nucleotide for inhibiting the expression of human circ_0001017 circular RNA and its application, characterized in that: the nucleotide specifically binds to the human circ_0001017 circular RNA, and the sequence of the nucleotide is determined by AUAGAUUACUUCGCACUGGUUCC A sequence or a complementary sequence of 18-23 consecutive nucleotide sequences consisting, in particular, comprising the sequences: AUAGAUUACUUCGCACUGG and AGAUUACUUCGCACUGGUUCC. The invention inhibits human circ_0001017 circular RNA, can effectively inhibit the expression of circ_0001017 circular RNA in A549 and MBA-MD-231 cells, and can increase its inhibition of growth and proliferation in combination with anti-tumor drugs, thereby effectively treating various tumors. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111218508-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111647597-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111647597-B |
priorityDate | 2019-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.