http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109706152-A

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
filingDate 2019-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_508116923f82099ffb58fa147688e028
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3c0c751c4e340bf02a33566095f7a91
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publicationDate 2019-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109706152-A
titleOfInvention A kind of siRNA for inhibiting the expression of circ_0001017 and its application
abstract The invention discloses a nucleotide for inhibiting the expression of human circ_0001017 circular RNA and its application, characterized in that: the nucleotide specifically binds to the human circ_0001017 circular RNA, and the sequence of the nucleotide is determined by AUAGAUUACUUCGCACUGGUUCC A sequence or a complementary sequence of 18-23 consecutive nucleotide sequences consisting, in particular, comprising the sequences: AUAGAUUACUUCGCACUGG and AGAUUACUUCGCACUGGUUCC. The invention inhibits human circ_0001017 circular RNA, can effectively inhibit the expression of circ_0001017 circular RNA in A549 and MBA-MD-231 cells, and can increase its inhibition of growth and proliferation in combination with anti-tumor drugs, thereby effectively treating various tumors.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111218508-A
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priorityDate 2019-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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