http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109694910-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4721 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate | 2018-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109694910-B |
titleOfInvention | Application of defensin HNP gene in the treatment of organ damage |
abstract | The invention discloses the application of defensin (HNP) gene in treating organ damage. The application of the defensin HNP gene in the present invention as a target for screening drugs, the drug is a drug for preventing, alleviating or/and treating the inflammatory response and organ damage caused by the increase of the defensin HNP; the defensin HNP gene The nucleotide sequence of the defensin HNP is shown in any one of SEQ ID NO:1-3, and the amino acid sequence of the defensin HNP is shown in any one of SEQ ID NO:4-7. The mechanism by which defensins (HNP) released by leukocytes lead to inflammatory responses and the role of defensins in inducing inflammatory damage to organs through specific direct and indirect receptors. The present invention confirms that the defensin and its direct and indirect receptor proteins can be applied to prevent, relieve or/and treat inflammatory response and organ damage caused by white blood cells. In addition, the discovery of the role of defensins and their direct or indirect receptor proteins in organ damage caused by inflammatory responses will provide new directions for further research. |
priorityDate | 2018-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 730.