http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109694357-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7eb9d223c849fb2d413ac8f7a87cd576 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-94 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-94 |
| filingDate | 2018-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7e9e5dcd14cae98997ed84c68cfbba4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1b423ac0eadc1a1a571317d67a8c123 |
| publicationDate | 2019-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109694357-A |
| titleOfInvention | A kind of preparation method of high-purity afatinib intermediate |
| abstract | The present invention provides a kind of preparation method of high-purity afatinib intermediate.This method comprises: the cyclization of 2- amino -4- fluobenzoic acid, nitrification, chloro are connect 3,-chloro- 4- fluoroaniline, reaction route is as follows: .Material of the present invention is cheap, easy to operate, and product purity is high, and easy to industrialized production. |
| priorityDate | 2018-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.