http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109692344-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-604 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-252 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-412 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-02 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-222 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-227 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08H1-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-12 |
| filingDate | 2019-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109692344-B |
| titleOfInvention | rH-BMP 2-containing bone repair material and preparation method and application thereof |
| abstract | The invention belongs to the field of biomedical materials containing active protein and the field of regenerative medicine, and particularly provides a bone repair material containing rH-BMP2, which comprises modified gelatin and rH-BMP 2. The material can be used for repairing bone injury. The invention provides a bone repair material containing rH-BMP2, which comprises the following components in percentage by mass: 21-5% of rH-BMP, 60-86% of modified gelatin, 5-20% of hydroxyapatite and 8-15% of calcium chloride. The bone repair material containing rH-BMP2 has improved mechanical property, and can be used as slow release carrier to realize great improvement in degradation/release time and reduce allergy. The effect which is obviously superior to that of chitosan and the prior similar material is obtained in both in-vitro release experiments and animal experiments. The cytotoxicity test also preliminarily proves the safety of the compound. |
| priorityDate | 2019-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 145.