http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109691435-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N1-0221 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N1-02 |
filingDate | 2019-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109691435-B |
titleOfInvention | Cryopreservation protective agent and simple cryopreservation method for hematopoietic stem cells |
abstract | The invention discloses a cryopreservation protective agent for hematopoietic stem cells and a simple cryopreservation method. After the DMSO content is reduced to 3 percent on the basis of the prior art, the cryopreservation survival rate of hematopoietic stem cells is obviously reduced, but the invention discovers that the freezing damage caused by the reduction of the DMSO content can be counteracted by adding the glycyrrizol into the freezing protective agent, the glycyrrol has the freezing protection effect on the hematopoietic stem cells, and the inhibition of the Caspase-3 expression can be a mechanism for exerting the freezing protection effect of the glycyrrol on the hematopoietic stem cells. |
priorityDate | 2019-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 77.