| abstract |
The invention provides an application of WDR12 gene in the inhibition and apoptosis of brain glioma cells, and relates to the technical field of molecular biology. The inventor's research proves that the expression of WDR12 gene is positively correlated with the grade of glioma, Knockout of WDR12 gene has significant effects on the proliferation, apoptosis and cell cycle of glioma cells. Therefore, the WDR12 gene can be used as a specific gene target for the inhibition and apoptosis of glioma cells, which provides a new theoretical basis for the development of targeted therapeutic drugs for glioma. |