http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109679969-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ab7f3ec544bfbffc49b3f13404daebb6 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-36 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-465 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31 |
filingDate | 2019-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e541ff396bc1ac7bc82fba5a67131772 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18c003f5d6463f38f69fe6169d5bb5d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_922d3a13e65efa33ddc461d9eacfce24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ad32b8f9f33cb9da3bbcb6ddf774029 |
publicationDate | 2019-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109679969-A |
titleOfInvention | Cell-synthesized genes involved in the regulation of ACT production in Streptomyces |
abstract | The present application belongs to the technical field of microbial fermentation engineering, and particularly relates to a gene related to the production of polyketide ACT (ACT) in Streptomyces sp. The application specifically relates to the application of cell-synthesized genes in the regulation of Streptomyces ACT production, and the cell-synthesized genes have a total of 7 genes; including: SCO1525 , SCO2097 , SCO2132 , SCO3150 , SCO4440 , SCO4878 , SCO5174 ; Has a regulatory effect on Streptomyces ACT production. The inventors mutagenized Streptomyces coelicolor M145, and screened the strains with changes in actiniodopsin production. The screened positive clones were identified by enzyme digestion, self-ligation and sequencing to locate the position of the transposon on the genome, and the spontaneous mutation gene was excluded based on the principle of multiple screening and positioning of the same gene, and finally the factors affecting the production of actinomycin were determined. Gene. |
priorityDate | 2019-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.