| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7d927148c7982a59521f5c2ed8ae37c0 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7052
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5169
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7052 |
| filingDate |
2018-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_647831de73841b4047fbb0cadafad172
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f07e1a7a41df53ccf6c5869fd6986abd |
| publicationDate |
2019-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-109678931-A |
| titleOfInvention |
A responsive small molecule peptide nano-drug carrier |
| abstract |
The invention provides a polypeptide whose structural formula is Ac-VVVVVVKKK-NH 2 , and discloses a construction, preparation method and application of a peptide nanometer drug-carrying carrier. The Ac-VVVVVVKKK-NH 2 polypeptide self-assembles in a PBS solution to form nanospheres According to the morphology, the polypeptide nanospheres can be used as drug-carrying carriers to embed fat-soluble drugs. The nanospheres formed by the self-assembly of the polypeptide molecules proposed in the present invention can be broken and collapsed into nanofibers through the addition of plasma amine oxidase, effectively releasing fat-soluble drugs, and are a kind of ideal nanometer drug-carrying materials, which have great effects on human life and health. important meaning. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110272471-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113024638-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110423266-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113024638-B |
| priorityDate |
2018-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |