http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109678788-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-60 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 |
| filingDate | 2019-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109678788-B |
| titleOfInvention | 1, 2-diaryl indole, derivative and synthetic method thereof |
| abstract | The application relates to 1, 2-diaryl indole, derivatives and a synthesis method thereof, and the technical scheme is that under the catalysis of secondary amine, an iodine reagent and a sulfoxide or sulfone reagent are used as additives, and in an organic solvent in an oxygen atmosphere, transition metal is not required to be added, so that the 1, 2-diaryl indole and the derivatives are generated. Compared with the prior art, the invention has the following advantages: 1) the required reagent has stable property, is convenient to store, is cheap and easy to obtain, and is beneficial to reducing the production cost; 2) the synthesis is carried out by a one-pot method, the economic advantages of the steps are very obvious, and the time and the labor are saved; 3) the regioselectivity is excellent, a product with a complex and changeable structure is prepared, and the generation of isomers which are difficult to separate is avoided; 4) transition metal is not needed, so that the pollution of the transition metal to products is eliminated; 5) the reaction takes oxygen as an oxidant and water as the most main byproduct, and is environment-friendly; 6) the whole reaction system is simple, reaction equipment is less, and the experimental operation is simple and convenient. |
| priorityDate | 2019-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 221.