http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109675065-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d9de52bba13e16028dffa8775e3f3f28 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-126 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1854 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-18 |
| filingDate | 2018-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7991c8b711468c1d957ecfa58d33536 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4dabdcc101e068cb65c9205eeed9df13 |
| publicationDate | 2019-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109675065-A |
| titleOfInvention | Nanomagnetic beads for T1 and T2 magnetic resonance dual-modality imaging and preparation method thereof |
| abstract | The invention relates to a nano-magnetic bead for T1 and T2 magnetic resonance dual-mode imaging and a preparation method thereof. The nano-magnetic bead comprises a nano-ferric oxide magnetic bead and a polymeric nano-bead wrapped on the outside of the nano-ferric oxide magnetic bead. Acrylic acid shell, when preparing, dissolving ferric salt and divalent ferrous salt in concentrated hydrochloric acid to obtain a salt solution, adding the salt solution to the polyacrylic acid aqueous solution, after mixing evenly, heating and refluxing under N2 environment, Then add concentrated ammonia water, and after the reaction is completed, cool, filter and purify to obtain the product. Compared with the prior art, the present invention provides a preparation method of ultra-small nano-magnetic beads for T1 and T2 magnetic resonance dual-modal imaging, which has simple process, mild reaction conditions, low cost, no pollution, and The contrast agent can be metabolized in vivo and can be used as a clinical magnetic resonance contrast agent. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112133553-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112133553-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021190573-A1 |
| priorityDate | 2018-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.