http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109666064-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-10 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08 |
| filingDate | 2018-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109666064-B |
| titleOfInvention | SALL4-RBBp4 compound blocking polypeptide and derivative antitumor polypeptide and application thereof |
| abstract | The invention relates to a polypeptide with the ability of targeted inhibition of SALL4-RBBp4 complex formation, an antitumor polypeptide and application thereof, wherein the amino acid sequence of the polypeptide with the ability of targeted inhibition of SALL4-RBBp4 complex formation is shown in SEQ ID NO. 1, and the polypeptide can be used for preparing antitumor drugs; the anti-tumor polypeptide comprises a structural domain for targeted inhibition of SALL4-RBBp4 complex formation and a transmembrane structural domain, the amino acid sequence of the structural domain for targeted inhibition of SALL4-RBBp4 complex formation is shown in SEQ ID NO:1, and the anti-tumor polypeptide can be used for preparing anti-tumor drugs. The anti-tumor polypeptide has obvious anti-tumor activity, and the cell-penetrating peptide structure domain of the anti-tumor polypeptide has no cytotoxicity. The anti-tumor polypeptide has no cytotoxicity to normal cells, and can be independently used as an anti-tumor medicament or used for assisting other treatment modes to perform auxiliary tumor treatment. |
| priorityDate | 2018-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.