abstract |
The invention discloses a1, 3, 4-thiadiazole heterocyclic compound with hedgehog pathway antagonist activity, which has a structure shown in a general formula I: the 1,3, 4-thiadiazole heterocyclic compound with the hedgehog pathway antagonist activity can block metastasis and regeneration of tumor cells through hedgehog pathway antagonism, and has an obvious anti-tumor effect. |