http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109662948-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2095 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2059 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 |
filingDate | 2017-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109662948-B |
titleOfInvention | Platelet aggregation inhibitor and preparation method thereof |
abstract | The invention discloses a platelet aggregation inhibitor and a preparation method thereof. The method comprises the following steps: (1) mixing crystal I clopidogrel hydrogen sulfate with a disintegrating agent, then adding a bonding agent for granulation, and drying and then finishing granules to obtain dry granules; (2) mixing the dry particles obtained in the step (1) with an anti-sticking agent to obtain mixed particles; (3) and (3) mixing the mixed granules obtained in the step (2) with a filler, then mixing with a glidant and a lubricant, tabletting and coating. The preparation method solves the sticking problem in the production process, simultaneously overcomes the stability problems of the degradation of active ingredients and the configuration transformation of products, and all the equipment used by the preparation method is common equipment in the pharmaceutical industry, is suitable for mass production, and has low production cost and high efficiency. |
priorityDate | 2017-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.