http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109661581-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2560-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-173845 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-9406 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6812 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate | 2017-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2023-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2023-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109661581-B |
| titleOfInvention | Methods and kits for the derivatization of biogenic amines |
| abstract | The present invention relates to analytical chemistry and in particular to devices and methods for the quantitative determination of derivatized biogenic amines, their precursors or their metabolites. Provided is a method for in situ derivatization of at least one biogenic amine, its precursors and/or its metabolites in an isolated aqueous sample, the derivatization comprising the steps of: (i) at a pH of 7.0 to In the presence of 9.0 phosphate buffer, the sample is contacted with a propionic anhydride/acetonitrile solution, and the amine moiety and/or the hydroxyl moiety of the biogenic amine or its metabolite are converted to form the propionyl group of the biogenic amine derivative; subsequently (ii) adding a carbodiimide compound and an electrophilic amine-containing compound to the reaction mixture obtained in step (i), and allowing the carboxylic acid moiety of the biogenic amine, its precursor and/or its metabolite to undergo Carbodiimide-mediated derivatization. |
| priorityDate | 2016-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 126.