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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4245
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4245
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04
filingDate 2017-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109651352-B
titleOfInvention Dimeric indole alkaloid compounds, preparation method thereof and application thereof in preparation of antibacterial drugs
abstract The invention belongs to the field of organic synthesis and medicinal chemistry medicines. In particular to dimeric indole alkaloid compounds with a structural general formula shown as I, a preparation method thereof and application thereof in preparing antibacterial drugs. The results of in vitro activity screening show that the compounds have stronger antibacterial activity, particularly have specific inhibition effect on gram-positive bacteria such as staphylococcus, bacillus, enterococcus and other strains and related drug-resistant strains thereof, and can be used as a lead compound for developing new antibacterial drugs.
priorityDate 2017-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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