http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109651333-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2018-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109651333-B |
titleOfInvention | 2-indol-3-yl-quinoline compound with anti-tumor activity and preparation method and application thereof |
abstract | The invention discloses a 2-indole-3-yl-quinoline compound with anti-tumor activity, a preparation method and application thereof, wherein the preparation route of the 2-indole-3-yl-quinoline compound is as follows: wherein R is 1 And R 2 Independently selected from hydrogen, alkyl, methoxy, ester group or halogen substituent, tetrahydroquinoline compounds, indole compounds, metal catalyst, acid and solvent react under the condition of oxygen to obtain 2-indol-3-yl-quinoline compounds, have good inhibition effect on K562 tumor cells and HeLa cells, and are expected to be used in medicaments for preventing and treating tumors. |
priorityDate | 2018-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 119.