http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109651319-B

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64
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filingDate 2019-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109651319-B
titleOfInvention Fluorescent probe based on coumarin carbazone derivative and preparation method and application thereof
abstract The invention provides a fluorescent probe based on coumarin carbazone derivatives, a preparation method and application thereof, and belongs to the field of organic synthesis. The coumarin carbazone derivative based on the invention can react with Cu 2+ Form stable complex with better Cu 2+ Ionic recognition Performance hydroxyethylpiperazine Ethanesulfonic acid (HEPES, 5 × 10) at pH 7.4 ‑3 mol/L DMSO with the volume ratio of 0.5 percent) buffer solution, and has remarkable AIEE property for Cu 2+ The ions show higher selective fluorescence recognition performance. Cu 2+ The addition of the probe solution can almost completely quench the green fluorescence of the probe solution, has a fluorescence attenuation effect, and can realize naked eye identification and detection. More importantly, the method can also be used for Cu in cells 2+ The fluorescence imaging detection of the ions has the characteristics of rapidness, simplicity, convenience, high sensitivity, low detection limit and strong selectivity, and has wide potential application value.
priorityDate 2019-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 30.