http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109646686-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-185 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0021 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-0033 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0084 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 |
filingDate | 2019-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109646686-B |
titleOfInvention | Application of metal iridium complex nano particle in nuclide excited phosphorescence imaging |
abstract | The invention relates to the field of nano materials and molecular imaging, in particular to application of a metal iridium complex solution and a nuclide solution in phosphorescence imaging after mixing. The concentration of the metal iridium complex solution is 0.05-10 mg/mL. The activity of the nuclide solution is 0.01-10 mCi. The invention improves the biocompatibility of the metal iridium complex by a liposome coating method, so that the metal iridium complex has good light stability, chemical stability and low cytotoxicity, changes the original phosphorescence imaging mode which can only be excited by an external excitation light source to generate strong background noise, expands the application of the metal iridium complex in radionuclide-excited phosphorescence, and has wide application prospect in the field of molecular images or. The invention provides a novel excitation mode of metal iridium complex phosphorescence, which is applied to fluorescence imaging, can acquire more optical signals, has high optical sensitivity, obtains better tissue penetrability, and can detect optical signals which cannot be detected by deeper tissues. |
priorityDate | 2019-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.