http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109646440-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4985 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4985 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-02 |
| filingDate | 2019-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109646440-B |
| titleOfInvention | Application of Cabotegravir in the preparation of anti-bovine infectious rhinotracheitis drug |
| abstract | The invention provides the application of Cabotegravir in the preparation of anti-bovine infectious rhinotracheitis medicine. It is found for the first time in the present invention that the compound Cabotegravir can effectively inhibit the proliferation of bovine infectious rhinotracheitis virus, and has less toxicity to cells. It has been proved by experiments that the median toxicity concentration (CC 50 ) of Cabotegravir to MDBK cells is greater than 100 μM, while the toxicity to bovine infectious rhinotracheitis virus is small. The median effective concentration (EC 50 ) of rhinotracheitis virus is 1.419 μM; the therapeutic index of Cabotegravir to bovine rhinotracheitis virus is greater than 70.47, indicating that it has the prospect of being developed into an anti-bovine rhinotracheitis drug, which is Cabotegravir It opens up new drug uses, and also lays the experimental foundation and provides new horizons for the development of efficient and specific anti-IBRV drugs. |
| priorityDate | 2019-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.