| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2df384e38c54aa0bbff49095e7dedcfd |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0052 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2019-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ac88ae0afc31e21eb1e6491394e3710
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a92874111a58be4b7e9baeb786bed334
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f3cc23ed296c8feff74461372aed611
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_169dfb34a0670d7cf6ddb9cc4454842c |
| publicationDate |
2019-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-109646398-A |
| titleOfInvention |
A kind of nano micelle and its preparation method and application |
| abstract |
A nano-micelle, preparation method and application thereof, relate to the technical field of photothermal agents. Nanomicelles are mainly formed by self-assembly of amphiphilic polymer block copolymers and porphyrin-type nitric oxide donors in water. The hydrophobic segments of the amphiphilic polymer block copolymers and porphyrin-type nitric oxide donors The bulk interacts to form an internal encapsulation material. Among them, the hydrophilic segment of the amphiphilic polymer block copolymer is methoxy-terminated polyethylene glycol, and the hydrophobic segment of the amphiphilic polymer block copolymer is protoporphyrin; The nitrogen donor is formed by the reaction of protoporphyrin diiodoethyl ester with Lucen's red salt. The nanomicelle can realize photothermal conversion while releasing nitric oxide under the irradiation of a single wavelength of light, and can effectively inhibit tumor growth. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112891533-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114931649-A |
| priorityDate |
2019-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |