abstract |
The invention discloses a compound of formula (I) or a salt thereof, wherein HET is heteroaryl selected from oxazolyl, pyrazolyl, imidazo [1,2-b ] and the like]Pyridazin-3-yl and pyrazolo [1,5-a ]]Pyrimidin-3-yl, wherein said heteroaryl is attached to the pyridyl of a compound of formula (I) through a carbon ring atom in the heteroaryl, and wherein said heteroaryl is substituted with 0 to 2R b Substitution; and R is 1 、R 3 And R b Are defined herein. Also disclosed are methods of using such compounds as IRAK4 modulators, and pharmaceutical compositions comprising such compounds. These compounds are useful for treating, preventing or slowing inflammatory and autoimmune diseases, or for treating cancer. |