http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109627228-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e6ab12b6da3f13f08aba045b87397852 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a64b653e07047b366b4103c0a7419e8c |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D305-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D305-10 |
| filingDate | 2017-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59af03aeb21edb8df7a9b7f84a59f610 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_597ec1c00fd01d85a79077a6c13c36cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1fd75e5867c1eacd6becd0c57c88f7ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_475a519eb89e2986bf7f0aa578fe16d1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab5d161675a3540b44c770d5e3f6be56 |
| publicationDate | 2019-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109627228-A |
| titleOfInvention | A kind of synthetic method of 3-oxetanone |
| abstract | The invention provides a method for synthesizing 3-oxetanone. The method comprises the following steps: deprotecting an intermediate by using an organic strong acid in an organic solvent I, neutralizing it with a weak base to be slightly alkaline, and concentrating and distilling off the solvent to obtain 3-oxetanol crude product, then under the condition that catalyst I, halide, alkali exist, utilize oxidant to oxidize 3-oxetanol, and then separate and purify to obtain 3-oxetanone product; The preparation method of the intermediate is as follows: using epichlorohydrin and glacial acetic acid as raw materials, using catalyst II to catalyze a ring-opening reaction, then adding vinyl ethyl ether under the condition of organic strong acid, carrying out the reaction of protecting group, and then under the condition of strong base The cyclization reaction was carried out under the following conditions to obtain the key intermediate solution. The method combines the preparation process of 3-oxetanol, does not need to purify 3-oxetanol, can save the purification steps of 3-oxetanol, and has the advantages of low raw material, short route and no danger The use of reagents, etc. |
| priorityDate | 2017-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 109.