http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109627226-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-141 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-42 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-42 |
| filingDate | 2019-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109627226-B |
| titleOfInvention | A kind of preparation method of 4-methyl-5-ethoxyoxazole |
| abstract | The invention relates to a preparation method of 4-methyl-5-ethoxyoxazole, a key intermediate of vitamin B6, and belongs to the technical field of preparation of raw materials. The preparation method of the 4-methyl-5-ethoxyoxazole of the present invention, firstly puts 4-methyl-5-ethoxy-1, 3-oxazole-2 into the hydrolysis reactor in a certain proportion successively -Ethyl carboxylate, toluene, drinking water and sodium hydroxide, stir and keep warm for reaction; liquid separation, the pH value of the water phase is adjusted to 1.0-2.5 with hydrochloric acid; organic solvent is added to the system obtained in the second step, 30-50 ℃ The temperature-controlled reaction is performed until no carbon dioxide is released; after the decarboxylation is completed, the pH value is adjusted to ≥9.0, the liquid is separated, and the organic phase is subjected to vacuum distillation to obtain the intermediate 4-methyl-5-ethoxyoxazole. The process operation is simple and safe, and it is easy to industrialize production. |
| priorityDate | 2019-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.