| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_140efb7e2a330be53d94bda6ad75cbe5 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-178 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate |
2018-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4703bce4b9fef7506ea2ae48492982b5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_448966547d45665208248cce7354fdfe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c07fc2b438853829247e2554ee76839
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14d818d901d596724949af41aab05342
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_deb3261aad0bcca96e5fba77dd99931b |
| publicationDate |
2019-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-109609630-A |
| titleOfInvention |
Molecular markers for early gastric cancer diagnosis and their applications |
| abstract |
The invention discloses a molecular marker for early gastric cancer diagnosis and its application. The molecular markers are exosomal miRNA exo-miR-92b-3p and/or exo-let7g-5p, as shown in SEQ ID NO: 1 and SEQ ID NO: 2 in the sequence listing respectively. The present invention finds for the first time that, compared with normal people, the content of exo-miR-92b-3p and exo-let7g-5p in the circulating blood of patients with early gastric cancer is significantly increased, which has higher sensitivity and higher sensitivity than the conventional tumor marker CEA index. specificity. Moreover, the combination of exo-miR-92b-3p and exo-let7g-5p or combined with CEA indicators can significantly improve the diagnostic rate. Therefore, exo-miR-92b-3p and/or exo-let7g-5p can be used as early gastric cancer. Reliable circulating biomarkers for early gastric cancer diagnosis. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110029169-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112266958-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113322322-A |
| priorityDate |
2018-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |