http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109608474-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1088 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-10 |
| filingDate | 2018-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109608474-B |
| titleOfInvention | Compound for detecting tyrosinase and preparation method and application thereof |
| abstract | The invention belongs to the field of biochemical engineering, and particularly relates to a preparation method and application of a compound FL-O-T for detecting tyrosinase. The structural general formula of the compound FL-O-T is as follows: wherein R is 1 、R 2 、R 3 Hydrogen, alkyl or other common substituents. The compound FL-O-T can be used as a fluorescent probe for detecting tyrosinase, and is synthesized by nucleophilic substitution reaction of fluorescein derivatives and m-hydroxybenzyl bromide. The compound FL-O-T is synthesized by a nucleophilic substitution reaction of a fluorescein derivative FT-OH and m-hydroxybenzyl bromide. The target compound has high chemoselectivity, can track and detect tyrosinase in vitro and in vivo, and successfully monitors the activity of the tyrosinase in cancer cells and zebra fish. |
| priorityDate | 2018-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 160.