http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109608471-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-10 |
| filingDate | 2018-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109608471-B |
| titleOfInvention | Synthesis method of chiral spiro oxindole compound |
| abstract | The invention relates to a method for synthesizing chiral spiro oxindole compounds, which comprises the following stepsThe following steps: under the action of alkali, a transition metal catalyst and a chiral ligand, a compound with a structure shown in formula (I) or formula (III) generates a compound shown in formula (II) or a stereoisomer thereof in a solvent through intramolecular carbon arylation reaction, and the chiral spiro oxoindole compound is obtained. The novel synthetic method has the advantages of simple and easily obtained raw materials, simple and convenient synthetic method, few synthetic steps and capability of obtaining the chiral spiro oxindole compound with extremely high optical purity in high yield. |
| priorityDate | 2018-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 93.