http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109596748-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-027 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5038 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-66 |
| filingDate | 2018-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109596748-B |
| titleOfInvention | Method for detecting metabolites of gandi capsules for treating diabetic nephropathy patients |
| abstract | The invention provides a method for detecting metabolites of a patient with diabetic nephropathy treated by a gandi capsule, which is characterized by comprising the following specific steps of S1, 1:1 selection of a test group and a control group; s2, collecting samples to be detected periodically; s3, processing the sample of S2, and carrying out UPLC-Q-TOF/MS separation analysis; s4, carrying out metabolic profile analysis on the UPLC-Q-TOF/MS spectrum data obtained in the S3 to obtain a data set; s5, constructing a partial least squares discriminant analysis model according to the data set obtained in S4; s6, constructing an S-PLOT load graph according to the model of the S5 component, calculating a VIP value, obtaining a corresponding P value at the same time, and screening out a metabolic marker capable of distinguishing a blank group from a sweet land capsule administration group under the condition that the VIP value is more than 1.0 and the P value is less than 0.05. The pharmacological mechanism of the gandi capsule for treating the diabetic nephropathy can be predicted by the method. |
| priorityDate | 2018-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 83.