http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109593723-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-02 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0662 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
| filingDate | 2018-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109593723-B |
| titleOfInvention | Mesenchymal stem cell for inhibiting immune reaction and preparation method and application thereof |
| abstract | The invention discloses mesenchymal stem cells for efficiently inhibiting immune response and a preparation method and application thereof. The preparation method of the recombinant mesenchymal stem cell comprises the following steps: reducing the expression quantity of microRNA-129 genes in the receptor mesenchymal stem cells to obtain recombinant mesenchymal stem cells; the receptor mesenchymal stem cell is an in vitro mesenchymal stem cell. The preparation method is simple to operate, convenient and practical, the obtained mesenchymal stem cells are immunosuppressive mesenchymal stem cells, the secretion capacity of immune factors is reduced, and the NO secretion capacity is obviously enhanced, so that the capacity of inhibiting inflammatory reactions (such as inflammatory enteritis) is enhanced. Therefore, the invention establishes a stable preparation method of the mesenchymal stem cells for efficiently inhibiting the immune response, and lays a foundation for the research and the application of the mesenchymal stem cells. |
| priorityDate | 2018-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 94.