abstract |
The invention belongs to the technical field of medicines, and discloses (1) activity and structure of a new terpenoid compound 1-5 derived from a fungus secondary metabolite, (2) a separation and purification preparation method and antibacterial activity of the compound 1-5, a structural formula of the compound 1-5, and (3) derivative analogues, wherein the compounds 1 and 3 have strong antibacterial activity on methicillin-resistant staphylococcus aureus, staphylococcus, escherichia coli producing ultra-broad spectrum β -lactamase, and pseudomonas aeruginosa. |