http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109589411-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5031 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2017-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109589411-B |
titleOfInvention | Carrier-free nano-drug delivery system and preparation method and application thereof |
abstract | The carrier-free nano-drug delivery system prepared by the invention greatly improves the drug-loading rate in a self-assembly mode, avoids toxic and side effects caused by the introduction of a nano-carrier, and has good biocompatibility and biological safety. Meanwhile, the introduction of the polydopamine effectively protects the adriamycin drug molecules from being released in advance in the blood transportation process, and further reduces the toxic and side effects of the anticancer drug on normal tissues. NH (NH) 4 HCO 3 The introduction of the compound realizes 'blasting type' release under the near-infrared photo-thermal induction condition, and improves the tumor treatment effect. The preparation method is simple, the reaction condition is mild, and the production and use cost can be reduced. It is expected that the carrier-free nano drug delivery system has good application prospect in the aspect of tumor treatment. |
priorityDate | 2017-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.